Scientists from the University of Granada and GENYO (Pfizer-University of Granada-Andalusian Government Centre for Genomics and Oncological Research), in a study led by Juan Carlos Rodríguez-Manzaneque, have demonstrated the significant role of a protein called ADAMTS1 in uveal melanoma, one of the rarest and most aggressive cancers that exist, which develops in the eye. Tumors […]
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Scientists reveal mechanism that causes irritable bowel syndrome
KU Leuven researchers have identified the biological mechanism that explains why some people experience abdominal pain when they eat certain foods. The finding paves the way for more efficient treatment of irritable bowel syndrome and other food intolerances. The study, carried out in mice and humans, was published in Nature. Up to 20% of the […]
Scientists find that brain cancer is linked to tissue healing
The healing process that follows a brain injury could spur tumour growth when new cells generated to replace those lost to the injury are derailed by mutations, Toronto scientists have found. A brain injury can be anything from trauma to infection or stroke. The findings were made by an interdisciplinary team of researchers from the […]
Scientists discover a key genetic driver of lymphomas
Mutations in proteins called histone H1, which help package DNA in chromosomes, are a frequent cause of lymphomas, according to a study led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and The Rockefeller University. The findings could lead to new approaches to treating these cancers. Scientists in recent years have observed that mutations in histone […]
Scientists develop mathematical index to distinguish healthy microbiome from diseased
What causes some people to develop chronic diseases such as rheumatoid arthritis, cancer and metabolic syndrome while others stay healthy? A major clue could be found in their gut microbiome—the trillions of microbes living inside the digestive system that regulate various bodily functions. To utilize the huge population of tiny organisms as a proxy for […]
Brazilian scientists develop COVID-19 accelerometer
Researchers at São Paulo State University (UNESP) in Araçatuba, Brazil, have developed a computational tool that acts like a “COVID-19 accelerometer,” plotting in real time the rate at which growth is accelerating or decelerating in more than 200 countries and territories. Available free of charge online, the application automatically loads the most recent notified case […]
Scientists raise concern over hydroxychloroquine study
Dozens of scientists have raised concerns over a large-scale study of hydroxychloroquine and chloroquine published in the Lancet that led to the World Health Organization suspending clinical trials of the anti-viral drugs as a potential treatment for COVID-19. Hydroxychloroquine, normally used to treat arthritis, has become one of the most high profile drugs being tested […]
Scientists sequence more than 1,000 COVID-19 genomes to aid pandemic response
Over 1,000 sequences of the coronavirus genome have now been produced as part of work done by scientists and clinicians from the University of Sheffield and Sheffield Teaching Hospitals NHS Foundation Trust. The data is a major milestone for their work as part of a UK consortium to map how COVID-19 spreads, behaves and mutates. […]
Scientists explore links between genetics, gut microbiome and memory
A new study is among the first to trace the molecular connections between genetics, the gut microbiome and memory in a mouse model bred to resemble the diversity of the human population. While tantalizing links between the gut microbiome and brain have previously been found, a team of researchers from two U.S. Department of Energy […]
Gene variant staves off Alzheimer’s in some people, scientists find
People with a gene variant that puts them at high risk for Alzheimer’s disease are protected from its debilitating effects if they also carry a variant of a completely different gene, Stanford University School of Medicine investigators report in a large new study. Their findings, to be published Apr. 13 in JAMA Neurology, suggest that […]