Unmarried patients with cancer are less likely to get potentially life-saving surgery or radiotherapy than their married counterparts, raising the concern that medical providers may be relying on stereotypes that discount sources of social support other than a current spouse. That’s the conclusion reached by the University of Delaware’s Joan DelFattore, a professor emerita of […]
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Researchers find alarming risk for people coming off chronic opioid prescriptions: Patients on chronic opioid prescriptions were 3x more likely to die of an overdose in the years that followed coming off opioids
With a huge push to reduce opioid prescribing, little is known about the real-world benefits or risks to patients. A recent study published in the Journal of General Internal Medicine found an alarming outcome: Patients coming off opioids for pain were three times more likely to die of an overdose in the years that followed. […]
Lower risk for heart failure with new type 2 diabetes drug
The new type of drugs for type 2 diabetes, the so-called SGLT2 inhibitors, are associated with a reduced risk of heart failure and death as well as of major cardiovascular events, a major Scandinavian registry study led from Karolinska Institutet reports in The BMJ. Cardiovascular disease is a serious complication of type 2 diabetes. The […]
Artificial intelligence could use EKG data to measure patient’s overall health status
In the near future, doctors may be able to apply artificial intelligence to electrocardiogram data in order to measure overall health status, according to new research published in Circulation: Arrhythmia and Electrophysiology, a journal of the American Heart Association. An electrocardiogram, also known as an EKG or ECG, is a test used to measure the […]
New efficient method for urine analysis may tell us more
Human urine contains hundreds of small molecules that tell us about our health, diet and well-being. Associate Professor Frans Mulder, in collaboration with the University of Florence, has been successful in developing a new method for analyzing the components of a urine sample. Using this method, the analysis becomes both cheaper and more accurate. The […]
Mutations linked to familial pancreatic cancer
Pancreatic cancer is one of the deadliest cancers with limited treatment options. It typically comes with an especially poor prognosis due to its lack of symptoms until advanced stages and its ability to resist many anticancer therapies. Identifying genes involved in its development may lead to earlier diagnoses and improved treatments. Now a research team […]
A novel method to characterize genes with high-precision in single cells
The analysis of gene products in cells is an important tool for diagnosing disease and the design of new active substances in biological and medical research. At Helmholtz Zentrum München, a method of targeted RNA sequencing (transcriptome analysis) has now been developed, which precisely detects the smallest amounts of gene transcripts in single cells. The […]
Brighter possibilities for treating blindness
Advances in preclinical research are now being translated into innovative clinical solutions for blindness, a review published in the 10th Anniversary Series of Science Translational Medicine depicts. The review authored by José Sahel, Jean Bennett and Botond Roska summarizes recent therapeutic strategies for treating blinding diseases which are very encouraging. Review summary Gene replacement or […]
Artificial intelligence boosts proteome research: Machine learning makes proteomics research more effective
Using artificial intelligence, researchers at the Technical University of Munich (TUM) have succeeded in making the mass analysis of proteins from any organism significantly faster than before and almost error-free. This new approach is set to provoke a considerable change in the field of proteomics, as it can be applied in both basic and clinical […]
Single dose of targeted radiotherapy is safe and effective for prostate cancer
A single high dose of radiation that can be delivered directly to the tumour within a few minutes is a safe and effective technique for treating men with low risk prostate cancer, according to a study presented at the ESTRO 38 conference. Radiotherapy traditionally involves a series of lower dose treatments that take place over […]