A new study, led by the University of California, Irvine (UCI), reveals how chronic inflammation promotes muscle fibrosis, which could inform the development of new therapies for patients suffering from Duchenne muscular dystrophy (DMD), a fatal muscle disease. Titled, “A Stromal Progenitor and ILC2 Niche Promotes Muscle Eosinophilia and Fibrosis-Associated Gene Expression,” the study was […]
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UK cancer patients more likely to die following COVID-19 than European cancer patients
Cancer patients from the UK were 1.5 times more likely to die following a diagnosis with COVID-19 than cancer patients from European countries. This is the finding of a study of over 1000 patients—924 from European countries and 468 from the UK—during the first wave of the COVID-19 pandemic. The research team, led by Imperial […]
Study examines antibody response to COVID-19 vaccination in patients with kidney failure
In a recent study, most patients with kidney failure who were undergoing hemodialysis developed a substantial antibody response following the vaccination with the Pfizer-BioNTech vaccine against COVID-19, but it was significantly lower than that of individuals without kidney disease. The findings will appear in an upcoming issue of CJASN. Individuals with kidney failure who are […]
FDA Approves Merck’s Keytruda (pembrolizumab) Plus Platinum- and Fluoropyrimidine-Based Chemotherapy for Treatment of Certain Patients With Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction (GEJ) Carcinoma
KENILWORTH, N.J.–(BUSINESS WIRE) March 23, 2021 — Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration (FDA) has approved Keytruda, Merck’s anti-PD-1 therapy, for the treatment of patients with locally advanced or metastatic esophageal or gastroesophageal junction (GEJ) (tumors with epicenter 1 to […]
More than 80% of intubated COVID patients die in Brazil
More than 80 percent of COVID-19 patients who have to be intubated in Brazil have died since the start of the second wave of infections ravaging the country, according to researchers. The mortality rate since February 15—83.5 percent—is far higher than in countries such as Mexico, Britain, Germany or Italy, highlighting how the South American […]
‘Painless’ glucose monitors pushed despite little evidence they help most diabetes patients
In the nation’s battle against the diabetes epidemic, the go-to weapon being aggressively promoted to patients is as small as a quarter and worn on the belly or arm. A continuous glucose monitor holds a tiny sensor that’s inserted just under the skin, alleviating the need for patients to prick their fingers every day to […]
Cancer trial participation does not eliminate disparities for poor patients
Even with access to a clinical trial, cancer patients living in the poorest neighborhoods in America have a nearly 30 percent greater chance of dying from their disease compared to the wealthiest patients, SWOG Cancer Research Network study results show. Published in the Journal of Clinical Oncology, the findings illustrate the stubbornly harmful effects of […]
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Model helps predict which patients will benefit most from PSMA PET scan
A new study led by researchers at the UCLA Jonsson Comprehensive Cancer Center helps identify which patients with prostate cancer will benefit most from the use of prostate-specific membrane antigen PET imaging, PSMA PET, a novel imaging technique that recently was approved by the U.S. Food and Drug Administration. By studying different variables and risk […]
Preventive blood thinning drugs linked to reduced risk of death in COVID-19 patients
Patients given preventive blood thinning drugs (prophylactic anticoagulants) within 24 hours of admission to hospital with COVID-19 are less likely to die compared with those who do not receive them, finds a study published by The BMJ today. Clinical trials are now underway to see if prophylactic anticoagulants could be an effective treatment for COVID-19. […]