A new coronavirus variant has been detected in the U.K., Nigeria and 11 other countries, including the U.S., according to a report by researchers at the University of Edinburgh. The variant, dubbed B.1.125, contains a mutation in the virus’s spike protein, which allows it to bind to and enter human cells. Scientists worry that because […]
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Virus surges anew in central Europe in face of new variants
Authorities in central Europe warned on Friday that they are seeing a surge in coronavirus cases across their region amid the discovery of new variants. The Polish health minister, Adam Niedzielski, said the first case of a variant first found in South Africa had been discovered in Poland, and that some 10% of all cases […]
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New potential therapy for Crohn’s disease in children
Scientists from the Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago demonstrated that a nanotherapy reduces intestinal inflammation and shrinks lesions in a rodent model of severe Crohn’s disease. This approach could become an alternative to biologic antibody therapies that carry many side effects, including increased risk of […]
Insights into the role of DNA repair and Huntington’s disease gene mutation open new avenues for drug discovery
Recent genetic data from patients with Huntington’s disease (HD) show that DNA repair is an important factor that determines how early or late the disease occurs in individuals who carry the expanded CAG repeat in the HTT gene that causes HD. The processes of DNA repair further expand the CAG repeats in HTT in the […]
New device decreases accidental cerebrospinal fluid leaks during epidural anaesthesia
Epidural anesthesia is a technique that requires great accuracy to avoid accidentally puncturing the dura mater, one of the three meninx that protect the central nervous system. The cerebrospinal fluid, which feeds the nervous system, is located under the dura mater. Leaks of this fluid can cause strong headaches that can be crippling and delay […]
The pandemic broke the CDC. New director will try to fix it.
The incoming CDC director has a lot of work to do, and she knows it. Dr. Rochelle Walensky said on Tuesday (Jan. 19) that over the last four years, scientists with the Centers for Disease Control and Prevention (CDC) “have been muzzled” and “science hasn’t been heard.” Walensky, formerly a professor of medicine at Harvard […]
New studies support blood test for early detection of Alzheimer’s disease
In three recent publications in Molecular Psychiatry, Brain and JAMA Neurology researchers from the University of Gothenburg provide convincing evidence that an in-house developed blood test for Alzheimer’s disease can detect the disease early and track its course, which has major implications for a potential use in clinical practice and treatment trials. “This is an […]
New treatment allows some people with spinal cord injury to regain hand and arm function
Almost 18,000 Americans experience traumatic spinal cord injuries every year. Many of these people are unable to use their hands and arms and can’t do everyday tasks such as eating, grooming or drinking water without help. Using physical therapy combined with a noninvasive method of stimulating nerve cells in the spinal cord, University of Washington […]
New insights on the role of the MLL4 gene in Kabuki syndrome
Scientists have known for years that mutations in the MLL4 gene can cause Kabuki syndrome, a rare developmental disorder. But a study published on Jan. 11 in Nature Communications illuminates new details regarding how this occurs. The research suggests that MLL4 controls the production of neurons that secrete growth hormone-releasing hormone (GHRH) in a part […]