Health Problems

Research uncovers mechanism behind epilepsy in Angelman syndrome

A key mechanism underlying neuronal dysfunction in Angelman syndrome (AS), a syndromic form of autism spectrum disorder, has—for the first time—been revealed through innovative research led by Duke-NUS Medical School and the National Neuroscience Institute (NNI) under the National Neuroscience Research Institute Singapore (NNRIS)—a joint venture combining neuroscience research expertise from both organisations. The finding […]

Health Problems

A mechanism capable of preserving muscle mass

Skeletal muscle is the most abundant tissue of the human body (about 40%) and it plays essential role in locomotion and vital functions (heart rate, breathing). During aging, in a large majority of individuals a loss of muscle mass, quality and strength occurs: this is called sarcopenia. This state, leading to disability and dependence, was […]

Health News

Researchers identify new mechanism to reduce inflammation

UT Southwestern researchers have identified two proteins that act as gatekeepers to dampen a potentially life-threatening immune response to chronic infection. The proteins—the transcription factors SIX1 and SIX2—activate cellular pathways required for fetal development and later switch to a new role in which they repress these pathways in adult immune system cells. The findings are […]

Health Problems

New mechanism of bone growth discovered

In a paper published in the journal Nature, an international research team led by researchers at Karolinska Institutet in Sweden reports that bone growth in mice takes place in accordance with the same principles as when new cells are produced in blood, skin and other tissue. This contradicts the previous understanding that bone growth depends […]