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Antibiotic may improve outcomes for depression in people with low level inflammation

King’s College London researchers have found evidence that minocycline, a widely used antibiotic with anti-inflammatory properties, gave greater improvement in depressive symptoms in patients with treatment resistant depression with low-grade peripheral inflammation. Improvement in depressive symptoms In a four-week randomised clinical MINDEP (MINocycline in DEPression) trial, 39 patients with major depressive disorder were recruited from […]

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Immune cells discovered in the lungs improve virus defense

A research team at the University of Basel has discovered immune cells resident in the lungs that persist long after a bout of flu. Experiments with mice have shown that these helper cells improve the immune response to reinfection by a different strain of the flu virus. The discovery could yield approaches to developing longer-lasting […]

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Teamwork, rapid data monitoring needed to improve nation’s heart health

For cardiovascular health to improve in the general population, healthcare systems will need to collect and assess treatment data, establish collaboration between researchers and healthcare professionals, and evolve patient care in real-time based on those data, according to “Achieving Optimal Population Cardiovascular Health Requires an Interdisciplinary Team and a Learning Healthcare System,” a new Scientific […]

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Arthritis drug may improve respiratory function in some patients with severe covid-19

A small study in Greece found that the clinically approved anti-inflammatory drug anakinra, used to treat rheumatoid arthritis, improved respiratory function in patients with severe coronavirus disease 2019 (COVID-19). The eight patients also had a condition called secondary hemophagocytic lymphohistiocytosis (sHLH), which is characterized by overactivation of the immune system and organ failure. One patient, […]

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New hope for ACL injuries: Adding eccentric exercises could improve physical therapy outcomes

People with anterior cruciate ligament injuries can lose up to 40% of the muscle strength in the affected leg––with muscle atrophy remaining a big problem even after ACL reconstruction and physical therapy. Now, a new University of Michigan study challenges conventional wisdom about which exercises are most beneficial during post-injury physical therapy, and findings suggest […]