King’s College London researchers have found evidence that minocycline, a widely used antibiotic with anti-inflammatory properties, gave greater improvement in depressive symptoms in patients with treatment resistant depression with low-grade peripheral inflammation. Improvement in depressive symptoms In a four-week randomised clinical MINDEP (MINocycline in DEPression) trial, 39 patients with major depressive disorder were recruited from […]
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Using VR training to boost the sense of agency and improve motor control
With Japan’s society rapidly aging, there has been a sharp increase in patients who experience motor dysfunctions. Rehabilitation is key to overcoming such ailments. A researcher from Tohoku University has developed a new virtual reality (VR) based method that can benefit rehabilitation and sports training by increasing bodily awareness and improving motor control. His research […]
Immune cells discovered in the lungs improve virus defense
A research team at the University of Basel has discovered immune cells resident in the lungs that persist long after a bout of flu. Experiments with mice have shown that these helper cells improve the immune response to reinfection by a different strain of the flu virus. The discovery could yield approaches to developing longer-lasting […]
The immunomodulatory activity of a drug would improve the efficacy of immunotherapy in breast cancer
Despite the success of immunotherapy in the treatment of cancers such as lung or melanoma, it is still not effective in breast cancers for being ‘cold’, with low infiltration of immune cells. Tumors use strategies to evade immune surveillance by reducing the infiltration of cells that could attack them or by attracting immunosuppressive cells. These […]
Teamwork, rapid data monitoring needed to improve nation’s heart health
For cardiovascular health to improve in the general population, healthcare systems will need to collect and assess treatment data, establish collaboration between researchers and healthcare professionals, and evolve patient care in real-time based on those data, according to “Achieving Optimal Population Cardiovascular Health Requires an Interdisciplinary Team and a Learning Healthcare System,” a new Scientific […]
Arthritis drug may improve respiratory function in some patients with severe covid-19
A small study in Greece found that the clinically approved anti-inflammatory drug anakinra, used to treat rheumatoid arthritis, improved respiratory function in patients with severe coronavirus disease 2019 (COVID-19). The eight patients also had a condition called secondary hemophagocytic lymphohistiocytosis (sHLH), which is characterized by overactivation of the immune system and organ failure. One patient, […]
New hope for ACL injuries: Adding eccentric exercises could improve physical therapy outcomes
People with anterior cruciate ligament injuries can lose up to 40% of the muscle strength in the affected leg––with muscle atrophy remaining a big problem even after ACL reconstruction and physical therapy. Now, a new University of Michigan study challenges conventional wisdom about which exercises are most beneficial during post-injury physical therapy, and findings suggest […]
Antioxidant supplements do not improve male fertility, study suggests
Antioxidant supplements do not improve semen quality among men with infertility, according to a new study supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health. The study also found that antioxidant supplements likely do not improve pregnancy and live birth rates. The […]
Study suggests later school start times reduce car crashes, improve teen safety
A study published online as an accepted paper in the Journal of Clinical Sleep Medicine found that later school start times were associated with a significant drop in vehicle accidents involving teen drivers. Researchers analyzed motor vehicle accident statistics involving adolescents in Fairfax County, Virginia, for two school years before and after the implementation of […]