Laughing gas, also known as nitrous oxide, has become popular in recent years. You’ll likely have spotted little silver canisters littered around streets, especially outside nightclubs. In medical settings the drug can be used for pain relief, anaesthetic and to relieve anxiety. But laughing gas is also used recreationally, something Priti Patel has expressed concerns […]
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MS sufferers in England and Northern Ireland lose out on ‘life-changing’ drug
We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info Trials show fampridine can improve walking ability in some patients. But a decision by the […]
Common prescription drugs (not themselves antibiotics) may increase risk of developing antibiotic resistance
New research presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) taking place online (9-12 July), suggests that three commonly prescribed classes of drugs that are not themselves antibiotics—proton pump inhibitors (PPIs), beta-blockers and antimetabolites—could lead to antibiotic resistant infections caused by bacteria from the Enterobacteriaceae family. These antibiotic resistant infections […]
Arthritis drugs tocilizumab and sarilumab reduce COVID deaths: study
Arthritis drugs tocilizumab and sarilumab reduce the risk of death and the need for ventilators among hospitalized COVID-19 patients, according to an analysis of nearly 11,000 patients published Tuesday. The study appeared in the Journal of the American Medical Association and prompted the World Health Organization (WHO) to recommend the use of the medicines, known […]
New analysis links distinct patterns of genetic mutations with OCD
In the first analysis of its kind, researchers at Columbia University Vagelos College of Physicians and Surgeons and several other institutions have linked distinct patterns of genetic mutations with obsessive-compulsive disorder (OCD) in humans. The work, published online June 28 in Nature Neuroscience, confirms the validity of targeting specific genes to develop new OCD treatments […]
How Aussie drugs in the pipeline could treat COVID-19
While widespread vaccination is key in our fight against COVID-19, people who are infected still need better treatment to improve their chance of survival and making a full recovery. Early on, the world had high hopes for a range of repurposed medications which had previously been approved to treat other conditions—including hydroxychloroquine, remdesivir and ivermectin—to […]
Change to Gilead assistance program threatens prep access, HIV advocates say
Dr. John Carlo is concerned that patients at Prism Health North Texas who rely on the health care safety net will soon be struggling even more to stay on PrEP, a medication that prevents HIV transmission. Carlo, chief executive officer of the clinic, which runs three locations in Dallas, offers free PrEP to roughly 250 […]
USP7 inhibitors could increase the anticancer effects of CDK1 compounds in cancer patients
Understanding the components that control cell division is fundamental to understanding how life works and how alterations in this delicate process can cause diseases such as cancer. It was precisely the discoveries of "key regulators of the cell cycle" and their implications for processes such as cancer, that won the British scientists R. Timothy Hunt […]
Small molecule inhibitors of SARS-CoV-2 identified by screening
Even as the vaccine rollout continues against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), seeking to bring an end to the coronavirus disease 2019 (COVID-19) pandemic, new variants emerge that show immune escape capabilities. Effective and safe drugs thus remain essential to treat severe infections with this virus. A new preprint, released on the […]
Do Artemisia annua L. compounds have SARS-CoV-2 antiviral potential?
Caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the ongoing coronavirus disease 2019 (COVID-19) pandemic has led to over 121.2 million cases and over 2.6 million deaths worldwide. An interesting new study, published in the Journal of Ethnopharmacology, examines the potential antiviral activity of compounds present in the plant Artemisia annua L. Study: Artemisia […]