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The European Union’s medicines agency on Monday began reviewing Merck’s COVID-19 treatment pill so that it can swiftly advise national drug authorities in the 27-nation bloc that want to begin using it before it gets official approval. The European Medicines Agency said in a statement that it will give “EU-wide recommendations in the shortest possible […]
Steve Doocy: Get the COVID-19 vaccine if you have chance, it will ‘save your life’ ‘Fox & Friends’ co-anchor Steve Doocy stresses the importance of Americans vaccinating themselves Coronavirus patients taking statins prior to hospitalization substantially reduced their odds of in-hospital death and severe COVID-19, researchers found, confirming earlier findings. Statin drugs are frequently used […]
When it comes to making eggs, female flies and female humans are surprisingly similar. And that could be a boon for women seeking better birth control methods, a UConn researcher reports in the July 5 issue of PNAS. There are about 61 million women of reproductive age in the US, and about 43 millions of […]
A drug currently used to prevent organ rejection in transplants could also reduce chemotherapy resistance in glioblastoma, according to a Northwestern Medicine study published in Brain. The drug prevents glioblastoma cells from using molecular plasticity to circumvent chemotherapy, and Northwestern Medicine investigators are currently working to translate these findings to the clinic, according to Atique […]
The new drug sotorasib reduces tumor size and shows promise in improving survival among patients with lung tumors caused by a specific DNA mutation, according to results of a global phase 2 clinical trial. The drug is designed to shut down the effects of the mutation, which is found in about 13% of patients with […]
By studying guppies, scientists at the University of Toronto and Florida State University found that behaviors affected by methylphenidate hydrochloride (MPH) – the active ingredient in stimulants such as Ritalin and Concerta used to treat ADHD—can be passed along to several generations of descendants. “We exposed male and female Trinidadian guppies to a low, steady […]
A new immune checkpoint inhibitor has proven effective in helping save the lives of advanced melanoma patients, a breakthrough that could extend to the treatment of other cancers. Relatlimab is the first immunotherapy treatment to target LAG-3, a protein in immune cells which reinvigorates and enhances the tumor fighting response. Immune checkpoint inhibitors targeting the […]
U.S. regulators have approved the first new drug in over a decade for children with ADHD, which causes inattention, hyperactivity and impulsivity. The Food and Drug Administration late Friday OK’d Qelbree (KELL’-bree) for treating attention deficit hyperactivity disorder in children ages 6 to 17. It comes as a capsule that’s taken daily. Unlike nearly all […]
An early clinical trial in individuals with the deadly brain cancer, glioblastoma, showed an experimental spherical nucleic acid (SNA) drug developed by Northwestern University scientists was able to penetrate the blood-brain barrier and trigger the death of tumor cells. This is the first time a nanotherapeutic has been shown to cross the blood-brain barrier when […]
Vanderbilt researchers have identified the protein receptor in specialized heart cells that, when removed, preserves cardiac function after a heart attack. This discovery has significant implications for survival after a heart attack, with a promising therapeutic development now underway at the Warren Center for Neuroscience Drug Discovery. The article, “Targeting 5-HT2B Receptor Signaling Prevents Border […]