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To date, scientists have identified 32 genetic mutations associated with an increased risk of Alzheimer’s disease, with BYU contributing to many of those discoveries. Finding those links is important foundational research, but it has been extremely challenging to figure out exactly how these genetic variants affect human biology and actually change risk for disease. A […]
Reprogramming a patient’s own skin cells to replace cells in the brain that are progressively lost during Parkinson’s disease (PD) has been shown to be technically feasible, reports a team of investigators from McLean Hospital and Massachusetts General Hospital (MGH) in the most recent issue of the New England Journal of Medicine. PD is the […]
Gluten intolerance is associated with increased mortality In a large study, an increased mortality for a number of causes of death in individuals with celiac disease compared with healthy people it was found. Therefore, those who suffer from a gluten intolerance have a 20 percent higher risk of dying from cardiovascular disease, cancer, or respiratory […]
In a summary of a recent guideline from the National Institute for Health and Care Excellence (NICE), published online Jan. 29 in The BMJ, recommendations are presented for the assessment and management of thyroid disease. In the summary, Melina Vasileiou, from the Royal College of Physicians in London, and colleagues present some of the most […]
(HealthDay)—Reduced myocardial blood flow (MBF) and myocardial perfusion reserve (MPR) are prognostic for patients with coronary artery disease, according to a study published online Feb. 14 in Circulation. Kristopher D. Knott, M.B.B.S., from University College London, and colleagues examined the prognostic significance of MBF and MPR in 1,049 patients with suspected and known coronary artery […]
In a study published in JAMA Network Open today, Kaiser Permanente scientists report that diabetes patients who used the Kaiser Permanente patient portal and mobile phone app improved their diabetes management outcomes. The large study, involving more than 111,000 patients, was unique in assessing the relationship between the use of online tools and medication adherence […]
Chronic kidney disease (CKD) affects 14 percent of adults in the U.S. There are several stages of CKD, but when it progresses to kidney failure, outcomes are quite poor, with those patients dying at a higher rate than patients with most advanced cancers. Patients who go on dialysis face both an exhausting treatment regimen and […]
Using a type of genetic screen that had previously been impossible in the mammalian brain, MIT neuroscientists have identified hundreds of genes that are necessary for neuron survival. They also used the same approach to identify genes that protect against the toxic effects of a mutant protein that causes Huntington’s disease. These efforts yielded at […]
A collaboration between scientists at Rutgers University and Scripps Research led to the discovery of a small molecule that may slow down or stop the progression of Parkinson’s disease. Parkinson’s, which affects 1 million people in the United States and over 10 million worldwide according to the Parkinson’s Foundation, is a neurodegenerative disorder with no […]
(HealthDay)—Kertisha Brabson’s mom rushed to the hospital after being told her adult daughter was acting out of her mind. “She was talking out of her head, dancing like she was at a concert,” recalls Kertease Williams. “She was trying to get out of the room. They had to have a nurse in her room around […]