Health News

Discovery of a potential new therapy for inflammatory arthritis

In a paper published today in the journal Science Translational Medicine, researchers at the Schroeder Arthritis Institute, part of University Health Network (UHN) in Toronto, have made a discovery that could lead to new treatments for axial spondyloarthritis (SpA), a painful and debilitating form of arthritis which affects 1-2% of Canadians and causes inflammation in […]

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Bone-loss discovery points to potential treatment for osteoporosis, rheumatoid arthritis

A new discovery about osteoporosis suggests a potential treatment target for that brittle-bone disease and for bone loss from rheumatoid arthritis. The findings from University of Virginia School of Medicine researchers and their collaborators help explain why specialized bone cells, called “osteoclasts,” begin to break down more bone than the body replaces. With more research, […]

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Discovery of potential new combination therapy for leukemia

WEHI researchers have discovered why some leukemia cells are resistant to new “SMAC-mimetic’ anti-cancer agents, a finding which could improve the use of these drugs in the clinic. The team discovered that the ‘drug pump’ protein MDR1 makes acute myeloid leukemia (AML) cells resistant to SMAC-mimetics, by rapidly pumping out the drug of the cells […]

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New discovery could lead to therapies for patients with Duchenne muscular dystrophy

A new study, led by the University of California, Irvine (UCI), reveals how chronic inflammation promotes muscle fibrosis, which could inform the development of new therapies for patients suffering from Duchenne muscular dystrophy (DMD), a fatal muscle disease. Titled, “A Stromal Progenitor and ILC2 Niche Promotes Muscle Eosinophilia and Fibrosis-Associated Gene Expression,” the study was […]

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Discovery shows how to treat heart attacks—new drug development underway

Vanderbilt researchers have identified the protein receptor in specialized heart cells that, when removed, preserves cardiac function after a heart attack. This discovery has significant implications for survival after a heart attack, with a promising therapeutic development now underway at the Warren Center for Neuroscience Drug Discovery. The article, “Targeting 5-HT2B Receptor Signaling Prevents Border […]

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Discovery of ‘thought worms’ opens window to the mind

Queen’s University researchers uncover brain-based marker of new thoughts and discover we have more than 6,000 thoughts each day. Researchers at Queen’s University have established a method that, for the first time, can detect indirectly when one thought ends and another begins. Dr. Jordan Poppenk (Psychology) and his master’s student, Julie Tseng, devised a way […]