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Cytosurge’s FluidFM Technology Facilitates Multiplex CRISPR Editing and Monoclonal Cell Line Development in Less Than Three Weeks

In collaboration with University Children's Hospital, Tübingen, the genomic loci of several genes were simultaneously targeted by a multiplexed FluidFM nano-injection into single CHO cells, directly delivering gRNA/Cas9 RNP complexes into the nucleus Cytosurge, a leading global provider for precision single cell manipulation, announced today that its pioneering, patented FluidFM nano-probe enabled CRISPR multiplexing to […]

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Discovery shows how to treat heart attacks—new drug development underway

Vanderbilt researchers have identified the protein receptor in specialized heart cells that, when removed, preserves cardiac function after a heart attack. This discovery has significant implications for survival after a heart attack, with a promising therapeutic development now underway at the Warren Center for Neuroscience Drug Discovery. The article, “Targeting 5-HT2B Receptor Signaling Prevents Border […]

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New tool outsmarts COVID-19 virus to help vaccine development

Melbourne researchers have developed a tool to monitor mutations that make it difficult to develop coronavirus (COVID-19) vaccines and drugs. Ensuring treatments remain effective as the virus mutates is a huge challenge for researchers. The powerful new tool harnesses genomic and protein information about the virus and its mutations to aid drug and vaccine development. […]

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Probing the genes that organize early brain development

When brains begin developing, there are a lot of moving parts—and when mutations happen in early neurodevelopment, it can lead to disorders like macrocephaly and autism. But scientists don’t know much about the ways that development goes askew, particularly in humans. That’s why Wei Zhang, a postdoctoral scholar and research associate at USC’s Center for […]

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NIH to fund testing and development of HIV vaccine

After decades of failing to develop an effective vaccine against HIV, the federal government has committed $129 million to a new effort led by Scripps Research. The National Institutes of Health award was announced Wednesday. It will fund development and testing of a multistage preventive vaccine. The work will be performed by the Consortium for […]