A pioneering study, released as a preprint on the bioRxiv* server, reports on the interaction of a tailored titanium oxide nanoparticle (NP) with the full-length severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 1 (nsp1). This should be of value in developing new therapeutic tools against coronaviruses that act by targeting their proteins. It […]
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USP7 inhibitors could increase the anticancer effects of CDK1 compounds in cancer patients
Understanding the components that control cell division is fundamental to understanding how life works and how alterations in this delicate process can cause diseases such as cancer. It was precisely the discoveries of "key regulators of the cell cycle" and their implications for processes such as cancer, that won the British scientists R. Timothy Hunt […]
Programmed Cell Death Protein 1 (PD1)
Programmed cell death protein 1 (PD1) is a protein that is preferentially expressed in the body’s immune B, T and NK cells. It is a transmembrane protein that binds to other proteins known as programmed death ligand 1 (PD-L1) and programmed death ligand 2 (PD-L2), which are members of a family of co-inhibitory/co-stimulatory molecules, known […]