Health News

Protein AKAP8 suppresses breast cancer metastasis

A protein naturally produced in the body has been found to suppress breast cancer metastasis in animal models of human tumors. Researchers led by Baylor College of Medicine also found that high levels of this protein, AKAP8, predicts a better survival for breast cancer patients. The findings, in the current edition of the journal Nature […]

Health News

Updated guidelines issued for ER, PgR testing in breast cancer

(HealthDay)—In an American Society of Clinical Oncology/College of American Pathologists updated guideline, published online Jan. 13 in the Archives of Pathology & Laboratory Medicine and the Journal of Clinical Oncology, recommendations are presented for estrogen and progesterone receptor (ER/PgR) testing in breast cancer. Kimberly H. Allison, M.D., from the Stanford University School of Medicine in […]

Health Problems

A new role for a triple-negative breast cancer target

Unlike almost every other organ, the mammary gland does not develop until after birth. And it’s unusually dynamic, shape-shifting during menstrual cycles, puberty, pregnancy, and lactation. These changes require energy. In a study using a new, genetically altered mouse model, researchers led by Rumela Chakrabarti of Penn’s School of Veterinary Medicine have uncovered a key […]

Health News

Drug that halves risk of breast cancers carries on working

Oestrogen-blocking drug that halves the risk of breast cancer in post-menopausal women ‘works for SEVEN YEARS after they stop taking it’ Anastrozole, prescribed under the brand name Arimidex, blocks oestrogen It halves the risk of breast cancer in postmenopausal women, studies show  Now, a study shows these effects last for a further seven years, totalling […]

Health Problems

Findings could identify aggressive breast cancers that will respond to immunotherapy

University of North Carolina Lineberger Comprehensive Cancer Center researchers have discovered a promising method to identify aggressive breast cancer tumors that will respond to drugs that unleash the immune system against cancer. The U.S. Food and Drug Administration recently approved a treatment that combines an immunotherapy drug and chemotherapy for triple negative breast cancer, but […]

Health Problems

Study finds certain drugs used to treat eye diseases excreted into human breast milk

Certain drugs used to treat retinal diseases are excreted into breast milk, raising possible safety concerns for developing infants, suggests a first-of-its-kind study led by St. Michael’s Hospital in Toronto and published in Ophthalmology. Ranibizumab and aflibercept are medications used to treat several retinal diseases. They contain an agent called anti-vascular endothelial growth factor (anti-VEGF), […]

Health Problems

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

Researchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the participation of collaborators from the Baylor College of Medicine (Houston) and the University Institute of Oncology of Asturias (IUOPA), publish today in Cancer Research a study where they relate the high number of copies of a chromosomal region with the appearance of resistance to a […]