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University of Virginia Cancer Center researchers have identified a gene responsible for the spread of triple-negative breast cancer to other parts of the body—a process called metastasis—and developed a potential way to stop it. Triple negative breast cancer (TNBC) is an aggressive form of breast cancer that accounts for 40,000 deaths in the United States […]
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Genetic modifier HDAC6 was found to control tumor growth and halt metastasis in triple-negative breast cancer in vivo, according to a new study published in the top-tier journal Cancer Research by investigators at the George Washington University (GW) Cancer Center. Immunotherapy—the use of drugs to stimulate one’s own immune system to recognize and destroy cancer […]
A type of drug known as a PARP inhibitor, already used to treat breast and ovarian cancer, may be useful in treating children with high-risk neuroblastoma—a common childhood tumor with a low survival rate. Neuroblastoma is a cancer in children which arises from nerve cells in either the chest or the abdomen. In some neuroblastoma […]
The same genes that greatly increase the risk of breast cancer in U.S. white women, including women of Ashkenazi Jewish descent, also greatly increase breast cancer risk among African American women. These genes include the BRCA1, BRCA2 and PALB2 genes, each of which was associated with a more than seven-fold risk of breast cancer, as […]
HEALTH NOTES: Women unhappy with the size and shape of their bust could delay breast cancer diagnosis since they’re less likely to carry out checks Body hang-ups could delay breast cancer diagnosis, according to a major survey. Women dissatisfied with the size and shape of their bust are less likely to self-examine, a vital step […]
Drinking just two cups of milk a day ‘can increase the risk of breast cancer in women by up to 80%’ NHS recommends adults consume lots of cow’s milk because it’s rich in calcium But Californian researchers say treat these guidelines ‘with caution’ after study They looked at 53,000 women over eight years and found […]
A protein naturally produced in the body has been found to suppress breast cancer metastasis in animal models of human tumors. Researchers led by Baylor College of Medicine also found that high levels of this protein, AKAP8, predicts a better survival for breast cancer patients. The findings, in the current edition of the journal Nature […]
(HealthDay)—In an American Society of Clinical Oncology/College of American Pathologists updated guideline, published online Jan. 13 in the Archives of Pathology & Laboratory Medicine and the Journal of Clinical Oncology, recommendations are presented for estrogen and progesterone receptor (ER/PgR) testing in breast cancer. Kimberly H. Allison, M.D., from the Stanford University School of Medicine in […]
Unlike almost every other organ, the mammary gland does not develop until after birth. And it’s unusually dynamic, shape-shifting during menstrual cycles, puberty, pregnancy, and lactation. These changes require energy. In a study using a new, genetically altered mouse model, researchers led by Rumela Chakrabarti of Penn’s School of Veterinary Medicine have uncovered a key […]