A strong ability in languages may help reduce the risk of developing dementia, says a new University of Waterloo study. The research, led by Suzanne Tyas, a public health professor at Waterloo, examined the health outcomes of 325 Roman Catholic nuns who were members of the Sisters of Notre Dame in the United States. The […]
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How the eyes might be windows to the risk of Alzheimer’s disease: Researchers say how quickly a person’s pupil dilates while taking cognitive tests
Alzheimer’s disease (AD) begins to alter and damage the brain years — even decades — before symptoms appear, making early identification of AD risk paramount to slowing its progression. In a new study published online in the September 9, 2019 issue of the Neurobiology of Aging, scientists at University of California San Diego School of […]
Migraine diagnoses positively associated with all-cause dementia
Several studies have recently focused on the association between migraine headaches and other headaches and dementia and found a positive migraine-dementia relationship. However, most of these studies have failed to simultaneously adjust for several common comorbidities, thus potentially introducing bias into their findings. The goal of the present study, which will be published in the […]
Artificial intelligence boosts proteome research: Machine learning makes proteomics research more effective
Using artificial intelligence, researchers at the Technical University of Munich (TUM) have succeeded in making the mass analysis of proteins from any organism significantly faster than before and almost error-free. This new approach is set to provoke a considerable change in the field of proteomics, as it can be applied in both basic and clinical […]
How mutations lead to neurodegenerative disease
Scientists have discovered how mutations in DNA can cause neurodegenerative disease. The discovery is an important step towards better treatment to slow the progression or delay onset in a range of incurable diseases such as Huntington’s and motor neurone disease — possibly through the use, in new ways, of existing anti-inflammatory drugs. The team of […]
Dermcidin may play role in the pathogenesis of skin disease hidradenitis suppurativa
Dermcidin, an anti-microbial peptide normally found in human sweat, may play a role in the pathogenesis of this chronic skin disease hidradenitis suppurativa (HS), according to a research team from the George Washington University (GW). Their findings were recently published in Clinical and Experimental Dermatology. HS is a chronic, recurrent inflammatory disease of the apocrine […]
Drugs to prevent stroke and dementia show promise in early trial
Treatments that prevent recurrence of types of stroke and dementia caused by damage to small blood vessels in the brain have moved a step closer, following a small study. The drugs — called cilostazol and isosorbide mononitrate — are already used to treat other conditions, such as heart disease and angina. This is the first […]
New software aims to reduce variability in ELISA biomarker tests: Researchers developed an accessible strategy to limit issues with commercial research biomarker testing kits
A new computational approach has been developed to reduce variability in common research biomarker tests, a promising step in improving the ability of biomedical researchers and basic scientists to reproduce data and facilitate more consistent results across laboratories and long-term projects. Researchers from Boston Medical Center (BMC) and Boston University School of Medicine (BUSM), developed […]
Voluntary control of brainwaves in deep brain of patients with Parkinson’s disease
Parkinson’s disease is associated with abnormal beta wave activity in the subthalamic nucleus (STN), but a direct connection between this activity and movement difficulties has not yet been established. A study group at Osaka University developed a neurofeedback system which enables patients with Parkinson’s disease to voluntarily control beta wave activity in their deep brain […]
The first spontaneous animal model of human hypophosphatasia uncovered
A research group led by Professor Hannes Lohi at the University of Helsinki and Folkhälsan Research Center has uncovered a new skeletal disease in dogs. The disease was recognized in the Karelian Bear Dog breed and associated with an autosomal recessive defect in the alkaline phosphatase gene, ALPL. In humans, ALPL defects cause hypophosphatasia, which […]